COVID-19 Information Center

For COVID-19 testing or vaccination information, please call the Florida Department of Health St. Lucie at (772) 446-8480. Open 7 days a week 8 am - 5 pm. For information about cases, testing, and hospitalizations can be found on the St. Lucie County COVID-19 Dashboard: Vaccination Information | Recover St Lucie

  1. City Updates for COVID-19
  2. Other Testing & Vaccine Sites
  3. COVID-19 Recovery Grants
  4. Community Resources
  5. Business Assistance
  6. Governor's Executive Orders
  7. News Flash
  8. Stay Connected
  9. Helpful Contacts


Contact: Public Information Officer
(772) 785-5838


St. Lucie County, FL The Florida Department of Health in St. Lucie reminds the public that the elderly and those with underlying medical problems like high blood pressure, heart problems and diabetes are more likely to develop serious illness.  Please review the information below to help prevent the disease from spreading to people in your home and community.



DOH St. Lucie encourages all residents to continue practicing public health preventative measures to slow the transmission of COVID-19, including: 

  • Maintaining healthy habits, like washing your hands frequently and covering your cough/sneeze to protect against respiratory germs like COVID or the flu.
  • Staying home when you are sick.
  • The Centers for Disease Control and Prevention (CDC) recommends wearing a mask indoors in areas of substantial or high community transmission, regardless of vaccination status.  St. Lucie County is currently considered a community of high transmission according to the CDC COVID Data Tracker.



DOH St. Lucie guidance remains – the vaccine is the most effective way to protect yourself from COVID-19. Vaccine benefits include:

  • Significantly reduces the risk of contracting the virus even if you are exposed.
  • Teaching your body how to fight the virus.
  • Reducing the risk of severe symptoms, hospitalization, and death if you contract the virus.
  • Minimizing the ability for the virus to spread, especially to our most vulnerable populations.
  • Fighting against emerging variants that can cause worse symptoms and spread.


DOH St. Lucie transfers vaccine to 51 local medical providers and there are dozens of retail outlets for eligible residents to receive vaccine.  Please visit for a list of COVID-19 vaccine providers in our area. Additionally, DOH St. Lucie offers vaccine daily at our health department located at 5150 NW Milner Drive, PSL, 34986.  Please visit for more information about COVID-19 vaccinations at our office.


On January 4, 2022, CDC updated their recommendation for when many people can receive a booster shot, shortening the interval from 6 months to 5 months for people who received the Pfizer-BioNTech COVID-19 Vaccine.  


On January 5, 2022, CDC endorsed the Advisory Committee on Immunization Practices’ (ACIP) recommendation to expand eligibility of booster doses to those 12 to 15 years old. CDC now recommends that adolescents age 12 to 17 years old should receive a booster shot 5 months after their initial Pfizer-BioNTech vaccination series. 



Monoclonal antibody treatments can prevent severe illness, hospitalization and death in high-risk patients who have contracted or been exposed to COVID-19.  CDR Maguire Health & Medical operates a Monoclonal Antibody Treatment Center at the St. Lucie County Fairgrounds – Building C, located at 15601 Midway Road in Fort Pierce, Monday-Friday from 9 a.m. to 5 p.m.  This site is only accepting appointments and proof of a positive COVID-19 test is required for treatment. Visit  to make an appointment. After creating your account, if no appointments are available, CDR Maguire encourages you to check back frequently, as each cancellation opens a new appointment.



On January 6, Florida Department of Health (Department) issued updated testing guidance and recommendations to maximize the benefits of COVID-19 testing in Florida. A copy of the full COVID-19 testing guidance can be found here.


Allied Health continues to provide COVID-19 testing with no out-of-pocket costs for residents Monday-Friday from 9 a.m. – 5:30 p.m. at the Gwenda Thompson Trades Career Center at 3855 S. U.S. Hwy. 1, Fort Pierce, FL.  No appointment is necessary.


St. Lucie County Public Schools offers COVID-19 testing for School District Employee and Students

  • Manatee Academy K8 OPEN M-F, 8:30 a.m. – 1:30 p.m.
  • Fort Pierce Central HS OPEN M-F, 8:00 a.m. – 1:00 p.m.


For more information on other testing providers in St. Lucie County residents can visit  I have attached a file of local testing sites with changes highlighted in yellow, and an Allied Health testing flyer you can share.

COVID-19 and Flu Guide for Seniors:

An informative guide for seniors that covers what is needed for home-proofing, best daily/weekly practices, how to disinfect packages and mail, step-by-step protocols for deep cleaning, and safety advice from health experts. Check it out here: Guide for Seniors: Home-Proofing for COVID-19 and the Flu